Progressive depletion of mtDNA in mitochondrial myopathy.
نویسندگان
چکیده
The authors studied seven patients with mitochondrial DNA (mtDNA) myopathy. Over time, there was a progressive depletion of mtDNA, which preferentially affected wild-type mitochondrial genomes. This suggests that loss of wild-type mtDNA is a major feature of mtDNA myopathy, and preventing wild-type mtDNA depletion has treatment implications.
منابع مشابه
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ورودعنوان ژورنال:
- Neurology
دوره 67 3 شماره
صفحات -
تاریخ انتشار 2006